Atenolol BP/USP

4-(2-HYDROXY-3-((ISOPROPYL)AMINO)PROPOXY)PHENYLACETAMIDE

Molecular Formula:  C14H23ClN2O3

Molecular Weight: 302.799 g/mol

Atenolol is used for Acute alcohol withdrawal, Classic angina pectoris, Thyrotoxicosis, Tremors, Prophylaxis of migraine and other conditions. This salt may also be used for purposes not listed in this medication guide. Detailed information related to Atenolol uses, side-effects, reviews, questions, interactions, and precautions is as follows:

Atenolol Uses

Atenolol is used for the treatment, control, prevention, & improvement of the following diseases, conditions and symptoms:

  • Acute alcohol withdrawal
  • Classic angina pectoris
  • Thyrotoxicosis
  • Tremors
  • Prophylaxis of migraine

Atenolol improves the patient’s condition by performing the following functions: Binding to and blocking the activation of adrenergic beta-1 receptors.

Atenolol is a selective β1 receptor antagonist, a drug belonging to the group of beta blockers (sometimes written β-blockers), a class of drugs used primarily in cardiovascular diseases. Introduced in 1976, atenolol was developed as a replacement for propranolol in the treatment of hypertension. It works by slowing down the heart and reducing its workload. Unlike propranolol, atenolol does not readily pass through the blood–brain barrier, thus decreasing the incidence of central nervous system side effects.

Atenolol is one of the most widely used β-blockers in the United Kingdom and was once the first-line treatment for hypertension. Atenolol is effective at reducing blood pressure, but recent studies indicate that it does not reduce the morbidity or mortality caused by hypertension, and may even increase mortality in some subgroups. This means that when people take this drug, they get better blood pressure numbers, but they still die of heart attacks and strokes, despite the lower blood pressure.

In addition, the role for β-blockers in general in hypertension was downgraded in June 2006 in the United Kingdom, and later in the United States, as they are less appropriate than newer blood pressure medications including calcium channel blockers, thiazide diuretics, angiotension converting enzyme (ACE) inhibitors, and angiotensin receptor blockers, particularly in the elderly.